HKeyBio offers a sophisticated platform for preclinical autoimmune disease research using nonhuman primate (NHP) models. These models provide a crucial link between rodent studies and human clinical trials, offering a higher degree of translational relevance due to their closer physiological and immunological similarity to humans. This guide outlines the key features and benefits of our NHP autoimmune disease models.
Study Design and Execution:
Our expert team collaborates with clients to design customized preclinical studies tailored to their specific research objectives. We offer guidance on:
Model Selection: Choosing the most appropriate NHP model based on the target disease and therapeutic mechanism of action.
Dosage and Administration: Optimizing drug delivery routes and schedules for optimal efficacy and safety.
Endpoint Analysis: Developing a comprehensive assessment plan that includes clinical scoring, immunological assays, imaging studies, and histopathological analysis.
Our dedicated NHP facilities and experienced veterinary staff ensure ethical and humane animal care, adhering to the highest standards of animal welfare.