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Heymann nephritis hāngū

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Nephropathy Membranous

● Nga tohu me nga take  

Ka puta te nephropathy membranous (MN) i nga reanga katoa engari ko te nuinga i waenga i nga tane, me te toharite o nga tau e kitea ana i te rima tekau me te ono tekau. Koia te tuarua me te tuatoru o nga take matua o te mate renal mutunga-waahi i waenga i nga mate glomerular tuatahi i Amerika me Uropi. 

Ko te MN he mate autoimmune, e whakaatu ana me te whakahekenga uaua i waenga i te podocyte me te membrane glomerular basement. Na te kino o te pono o nga podocytes, ka ngaro te nui o te pūmua i roto i te mimi. Ko te proteinuria taumaha ka pa mai te hypoalbuminemia, anasarca, me te hypercoagulability. Ma te mau tonu o te proteinuria, tata ki te 40-50% o nga turoro ka mate te mate renal i roto i te tekau tau. 


Membranous nephropathy(1)-8

Ronco P, Beck L, Debiec H, et al. Nephropathy membrane. Nat Rev Dis Primers. 2021;7(1):69. I whakaputaina 2021 Sep 30. doi:10.1038/s41572-021-00303-z


 ● Tauira kei te waahi 【Rā➡Nga Tauira】

Passive heymann nephritis (PHN)

【Mechanism】Heymann Nephritis Tauira, he mea hanga e Heymann, he tauira kararehe puāwaitanga mo Membranous Nephropathy, kei roto i te Tauira nephritis Active me te Passive nephritis. Ko te tauira Passive Heymann Nephritis e whakaawehia ana e te anti-Fx1A(mai i te Proximal renal tubular epithelium) serum, e whakaatu ana i te BUN serum teitei, te pūmua mimi me nga huringa pathological whatukuhu, e tino rite ana ki te mate nephropathy membranous tangata.

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10422edd67dc165df2969d38cfc35f7被动型海曼肾炎模型PHN-20230204_20240617150148





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