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Moram typus hypersensitivity reactionem

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Moram Type hypersensitivity (DTH)

● Symptomata et causas

Definitio: cellula-mediatos immunitatem definitur ut prodest exercitum responsione propria per expanded population specifica T cellulis, quod in conspectu antigens, producere cytokines localiter. In activation et cooptatione cellulis in an area inflammatio est a crucial gradum in progressionem DTH respondeo.

Cellular et moceular mechanism: DTH est immunologically processus similis cellula-mediata immunitatem, involving T cellulis et cytokines. CD4 T adiutorium (Th) I cellulis, differentiated a rustica th cellulis ab il-XII et II-XVIII produci ex macrophages, ludere a regulatory in expressio γ generatur per Th1 et Naturalis interferon cellulis. Macrophages cumulare ad locum DTH et facti activated per CD4 Th1 cellula-Cytokine, macrophage axis. Sed DTH ducit ad pathologic respondeo, ut granulomatous inflammatio, calcification, caseation necrosis et cavum formationem. Granulomas solet formare ut propter perseverare a Nondegradable productum vel sicut effectus DTH respondeo. DTH est etiam requiritur ad exercitum defensionem contra etiologic agentibus, ut Mycobacterium tuberculosis. Et expressio cellula-mediata immunitatem / DTH est a geminus ancipitem gladio, qui potest conferre ad utrumque alvi de etiologic agente et TEXTUS damnum.

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Typus IV Hypersensitivity reactionem vel moratus genus hypersensitivity (DTH), March 20,2018 Online Biology notas.

● exempla in loco 【Date➡models】

● Oxa adductus DTH Model in C57BL / VI MICE

【Mechanism】 moratus-genus hypersensitivity (DTH) est utile aditus ad aestimandis cellula mediata immune respondeo consociata cum Th1 reactivity. DTH reactionem dividitur in affectionem et efferent augmenta. Per afferent tempus huius exemplar, mures typically immunized in iniectio cum specifica hapten aut antigen in chemica reactive status et emulsified cum adjuvically. Efferent phase typically initiantur 5-12 dies post sensitization, quibus ante sensitized mures sunt impugnentur aut subcutaneus footpad iniectio aut intradermal aurem iniectio. DTH responsio ad evaluated XXIV H Post provocare.

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