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Atopic Dermatitis

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Product Description

Atopic Dermatitis (AD)

● Symptomata et causas

Atopic Dermatitis aegris clinically praesens cutis erythematous plaques, eruptio, elevatur Serum IGE et T adiutorium cellula type II (Th2) Cytokine campester, ut IL-IV et II-XIII. Microscopically, atopic Dermatitis aegris etiam ostende epidermal hyperplasia et cumulus mast cellulis et th th2.

In aliquibus, atopic DERMATITIS est ad a gene variation qui afficit cute facultatem providere tutela. In aliis, atopic DERMATITIS causa nimia bacteria Staphylococcus aureus cutem.

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Guttman-Yassky E, Dhingra N, Leung d. Novum era de biologic therapeutics in atopic DERMATITIS. Peritus Opin Biol. MMXIII; XIII (IV) 549-561.

● exempla in loco 【Date➡models】

● DNCB adductus ad exemplar

【Mechanism】 homicidia sunt parva moleculae irritants quod ligare ad proteins et elicit an immune responsio et longum esse solebat studere allergic contactus DERMATITIS (ACD). Repetita hapten challenges perturbare ad cutis obice, combined cum th2-biased immune responsio.

Plerique happy, ut 2,4-dinitrochlorobenzenen (dncb) et oxazolone (oxa), inducere a responsione subcinctus a TH1 ad TH ^ ut Cutis DERMATITIS ad ATOPIC DERMATITIS, sicut cutis laesum.

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● Oxa adductus ad exemplar

【Mechanism】 homicidia sunt parva moleculae irritants quod ligare ad proteins et elicit an immune responsio et longum esse solebat studere allergic contactus DERMATITIS (ACD). Repetita hapten challenges perturbare ad cutis obice, combined cum th2-biased immune responsio.

Plerique happy, ut 2,4-dinitrochlorobenzenen (dncb) et oxazolone (oxa), inducere a responsione subcinctus a TH1 ad TH ^ ut Cutis DERMATITIS ad ATOPIC DERMATITIS, sicut cutis laesum.

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● Mc903 adductus ad exemplar

【Mechanism】 Mc903 (Calipotriol) est active Vitaminum D Analog non afficiens calcium metabolismi et dictum pro PSORIASIS aegris. Inducit irritans cutis inflammatio in aliqua psoriasis aegris ut latus effectus.

In mures mc903 upregulat TSLP et inducit atopic morbus-sicut cutis inflammatio in tslp-dependens modo. Collectively, in Mc903 Model sino nobis ad explorandum quam type II cutis inflammationes sunt initiatur a TSLP et ad resolvere partes variis immunes cellulis maxime in mane periodum inflammationes.

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● Fitc adducti Balb / C ad Model

【Mechanism】 Mures ostendit normalis migratio et cutis Dendritic cellulis et inductione hapten-specifica T cellulis in sensitisation tempus FitC-adductus ad, et normalem inductionem loci inflammatio in Elicitation tempus FitC-adductus ad. In alia manu, qui mures ostendit reducitur scalpendi frequency et durationem in Fitc-adductus ad.

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