Autoimmune Disease Animal Models-Small Animals

HKeyBio offers a comprehensive suite of preclinical services utilizing small animal models for autoimmune disease research.  These models are invaluable tools for understanding disease mechanisms, evaluating drug efficacy, and advancing therapeutic development.  Our expertise spans a wide range of autoimmune conditions, providing researchers with reliable and customizable solutions.  This guide outlines the key aspects of our small animal model services.

Model Development and Characterization:

We offer a diverse portfolio of over 200 established rodent models encompassing more than 50 types of autoimmune diseases. These models include, but are not limited to, those for:

• Skin-Related Diseases: Psoriasis, Atopic Dermatitis

• Joint-Related Diseases: Rheumatoid Arthritis

• Kidney-Related Diseases: Lupus Nephritis

• Digestive System Diseases: Inflammatory Bowel Disease (IBD)

• Respiratory Diseases: Asthma

• Eye-Related Diseases: Uveitis

• Neurological Diseases: Multiple Sclerosis (EAE model)

• Systemic Diseases: Systemic Lupus Erythematosus (SLE)

Each model is meticulously characterized to ensure it accurately reflects the human disease's key pathological features, including clinical symptoms, immunological profiles, and disease progression. This rigorous characterization allows for reliable and reproducible results, crucial for robust preclinical studies.