Experimental Autoimmune Neuritis (EAN)

HKB's Mouse Experimental Autoimmune Neuritis Models provide pharmaceutical researchers with robust platforms for investigating Guillain-Barré syndrome and related peripheral neuropathies. Our validated rodent models utilize P0 or P2 peptide immunization to replicate key features of EAN including demyelination of peripheral nerves, inflammatory infiltrates, and progressive weakness. These models support evaluation of immunomodulatory agents, neurotrophic factors, and approaches targeting peripheral nerve inflammation and repair.