Type 1 Diabetes (T1D)

HKB's Mouse Type 1 Diabetes Models provide pharmaceutical researchers with robust platforms for investigating autoimmune destruction of pancreatic beta cells. Our validated rodent models include NOD mice, multiple low-dose streptozotocin induction, and T-cell transfer models representing various stages of autoimmune diabetes development. These models support evaluation of antigen-specific tolerance approaches, B-cell depleting agents, and beta cell regenerative strategies.