Chemotherapy Induced Peripheral Neuropathy (CIPN)

HKB's Mouse Chemotherapy-Induced Peripheral Neuropathy Models provide pharmaceutical researchers with robust platforms for investigating this common dose-limiting side effect of cancer chemotherapy. Our validated rodent models utilize paclitaxel, vincristine, oxaliplatin, or bortezomib treatment to replicate the sensory neuropathy characteristic of CIPN including numbness, tingling, and pain. These models support evaluation of preventive agents, neuroprotective compounds, and symptomatic treatments for CIPN.