HKB's Mouse Uveitis Models provide pharmaceutical researchers with robust platforms for investigating inflammatory diseases of the eye. Our validated rodent models include experimental autoimmune uveitis (EAU) using IRBP or S-antigen, and endotoxin-induced uveitis (EIU) models representing various uveitis phenotypes. These models support evaluation of corticosteroid-sparing agents, anti-TNF biologics, and novel immunomodulatory approaches targeting ocular inflammation. Comprehensive endpoints include clinical ophthalmic scoring, fundoscopic assessment, and histopathological analysis.
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HkeyBio is a China-based, globally-focused preclinical CRO dedicated exclusively to autoimmune and allergic diseases, with a unified service network across Asia, the Americas, Europe and Australia.