Expert Of Animal Models In Autoimmune Diseases

HKeyBio is your preclinical CRO partner especially in autoimmune diseases field.

HKeybio offers more than 100 autoimmune-disease animal models in 7 categories relying on the rodent labs in Suzhou and non-human primate labs in Guangxi. These models can be used in in-vivo studies relevant to various pathogeneses and clinical subtypes of dozens of autoimmune diseases.

Your Consultant Of Drug Development Strategy Based On Drug Targets & Clinical Features Of Diseases

HKeybio has successfully helped our customers in pre-IND studies in China and abroad. We have experience in hundreds of drugs or therapies such as small molecules, mAbs, multispecific antibodies, ADCs, cell and gene therapies. We work 24×7 and will initiate your studies in 7 days.

Professional Animal Model Services

Inflammatory bowel disease View More

Inflammatory Bowel Disease-NHP View More

Autoimmune hepatitis View More

Systemic Sclerosis-NHP View More

Uveitis View More

Eosinophilic gastroenteritis View More

Idiopathic pulmonary fibrosis View More

Vitiligo View More

Urticaria View More

T cell dependent antibody response View More

Psoriasis View More

Chronic graft-versus-host disease View More

Acute graft-versus-host disease View More

Psoriatic Arthritis View More

Juvenile Idiopathic Arthritis View More

Cirrhosis View More

Systemic Lupus Erythematosus View More

Idiopathic thrombocytopenic purpura View More

Systemic Sclerosis View More

Sjogren's syndrome View More

KNOWLEDGE OF DISEASES

Disease Mechanism Disease

Characterization

Animal Model

Model Analysis

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EXPERIENCED IN PHARMACEUTICS

Study Design Experience
Communication
Documents For IND Registration

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PACKAGED SOLUTION

PK, PD, Tox Research
PK/PD, TK Evaluation
Integrated Pre-Clinical Study Plan

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PRECISE PROBLEM SOLVING

Target Based Biomarker Development
Unique Requirement Of Novel Drugs

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High-Tech Enterprise Specializes In Autoimmune Animal Models

HKeybio is a Contract Research Organization (CRO) specializing in preclinical research within the field of autoimmune diseases. The company operates a small animal and detection test facility in Suzhou Industrial Park, as well as a non-human primate test base in Guangxi. The founding team members each have extensive preclinical experience, with backgrounds in large international pharmaceutical companies totaling nearly 20 years.

+ years

Of experience in new drug development from our core team

Validated animal models

relevant to

Autoimmune-disease

Medicine Solutions With Personalized Customization

PRE-CLINICAL

RESEARCH

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Novel DDS Antibodies Cellular

Novel DDS

Client Background: Our client is a pharmaceutical company that has developed a novel compound designed to target mitochondrial damage-related autophagy and possess neuroregenerative properties. The client aims to explore the potential therapeutic effects of their compound in an autoimmune-mediated disease.

Problem Statement: The client sought to establish the efficacy of their compound in appropriate neurologically related autoimmune diseases.

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Antibodies

Client case: Development of a Novel Antibody Drug Targeting IL-25 for Atopic Dermatitis(AD).

Client: A pharmaceutical company developing a new antibody targeting the IL-25 pathway for the

treatment of AD

Objective: To establish the efficacy and safety of the new anti-IL-25 antibody in preclinical models of atopic dermatitis, compared to a standard positive drug control.

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Cellular
Therapy

Client case: Development of a Novel Antibody Drug Targeting IL-25 for Atopic Dermatitis(AD).

Client: A pharmaceutical company developing a new antibody targeting the IL-25 pathway for the
treatment of AD

Objective: To establish the efficacy and safety of the new anti-IL-25 antibody in preclinical models of atopic dermatitis, compared to a standard positive drug control.
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Gene
Therapy

Client case: Development of a Novel Antibody Drug Targeting IL-25 for Atopic Dermatitis(AD).

Client: A pharmaceutical company developing a new antibody targeting the IL-25 pathway for the
treatment of AD

Objective: To establish the efficacy and safety of the new anti-IL-25 antibody in preclinical models of atopic dermatitis, compared to a standard positive drug control.
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XDCS

Client case: Development of a Novel Antibody Drug Targeting IL-25 for Atopic Dermatitis(AD).

Client: A pharmaceutical company developing a new antibody targeting the IL-25 pathway for the
treatment of AD

Objective: To establish the efficacy and safety of the new anti-IL-25 antibody in preclinical models of atopic dermatitis, compared to a standard positive drug control.
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Small
Moleculars

Client case: Development of a Novel Antibody Drug Targeting IL-25 for Atopic Dermatitis(AD).

Client: A pharmaceutical company developing a new antibody targeting the IL-25 pathway for the
treatment of AD

Objective: To establish the efficacy and safety of the new anti-IL-25 antibody in preclinical models of atopic dermatitis, compared to a standard positive drug control.
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Vaccines

Client case: Development of a Novel Antibody Drug Targeting IL-25 for Atopic Dermatitis(AD).

Client: A pharmaceutical company developing a new antibody targeting the IL-25 pathway for the
treatment of AD

Objective: To establish the efficacy and safety of the new anti-IL-25 antibody in preclinical models of atopic dermatitis, compared to a standard positive drug control.
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Microbiota

Client case: Development of a Novel Antibody Drug Targeting IL-25 for Atopic Dermatitis(AD).

Client: A pharmaceutical company developing a new antibody targeting the IL-25 pathway for the
treatment of AD

Objective: To establish the efficacy and safety of the new anti-IL-25 antibody in preclinical models of atopic dermatitis, compared to a standard positive drug control.
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Not Only A Supplier But Also Your Reliable Target Validation Partner

What is PSO Model?

2024-08-22

The Pso (Psoriasis) model is a critical tool in the field of dermatological research, particularly for understanding and developing treatments for Psoriasis. Psoriasis is a chronic autoimmune skin disease characterized by red, itchy, and scaly patches. The Pso model, which includes various animal mo

2024-08-22

三级分类_Systemic-Lupus-Erythematosus-(SLE)--副本-.jpg

Insights into dsDNA's Role in SLE Model Studies

2024-10-29

Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the production of autoantibodies and widespread inflammation. One of the pivotal components implicated in the pathogenesis of SLE is double-stranded DNA (dsDNA). Understanding the role of dsDNA in SLE model studies i

2024-10-29

How Are Animal Models Revolutionizing SLE Model Research?

2024-08-15

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can affect virtually any organ system, leading to a wide range of symptoms and complications. Understanding this complex disease is a challenge that many researchers have faced over the years. The introduction of animal models i

2024-08-15

Professional Animal Model Services

High-Tech Enterprise Specializes In Autoimmune Animal Models

Medicine Solutions With Personalized Customization

Not Only A Supplier But Also Your Reliable Target Validation Partner

What is PSO Model?

Insights into dsDNA's Role in SLE Model Studies

How Are Animal Models Revolutionizing SLE Model Research?

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