Acute graft-versus-host disease

Graft-versus-host Disease (GVHD) 

● Symptoms and Causes  

Depending on which organs the immune system attacks, GvHD can cause symptoms ranging from rash, diarrhea, and hepatitis to potentially life-threatening bacterial, fungal, viral, or parasitic infections. 

Haemopoietic-cell transplantation (HCT) is an intensive therapy used to treat high-risk haematological malignant disorders and other life-threatening haematological and genetic diseases. The main complication of HCT is graft-versus-host disease (GVHD), an immunological disorder that affects many organ systems, including the gastrointestinal tract, liver, skin, and lungs. 

doi: 10.1136/archdischild-2013-304832. Epub 2014 Jul 12.